Sequence Data

  • Genomic context sensitizes regulatory elements to genetic disruption - GEO GSE241708
  • Synthetic regulatory genomics uncovers enhancer context dependence at the Sox2 locus - GEO GSE206863
  • Genomic context sensitivity of insulator function - GEO GSE179485
  • A versatile platform for locus-scale genome rewriting and verification - GEO GSE159488
  • DNase-seq profiling of Saos-2 and U2OS cell lines - GEO GSE142160
  • NYU Langone SARS-CoV-2 Sequencing Team - SRA PRJNA650245
  • DNase-seq profiling of hybrid mouse cells and tissues - GEO GSE156692

Additional Resources for Publications

Protocols

Tools

Reagents

News

February 2025
André's manuscript on using synthetic regulatory genomics to train deep learning models is now on bioRxiv.

January 2025
Matt is grateful to receive the Irma T. Hirschl/Monique Weill-Caulier Career Scientist Award.

December 2024
The lab has been awarded an R01 from NIMH to study the role of repeats in the genetics of psychiatric disorders.

May 2024
Raquel Ordoñez's paper on enhancer swapping at the Igf2/H19 and Sox2 loci has published in Molecular Cell.

March 2024
Raquel Moya has posted a preprint on the CACNA1C intron 3 repeat, in collaboration with the Tsien lab. Raquel will also be defending her thesis this month!

March 2023
Our manuscript using synthetic regulatory genomics to show how enhancers work together at Sox2 has been published in Molecular Cell.